Toledo vs. Miami (Ohio) MACtion odds, line: 2025 college football picks for Week 12 predictions from proven model

Teams battling for positioning in a wide open Mid-American Conference race clash when the Toledo Rockets face the Miami (Ohio) RedHawks in MACtion on Wednesday night. Toledo is coming off a 42-3 win over Northern Illinois last week, while Miami dropped a 24-20 decision at Ohio. The Rockets (5-4, 3-2 MAC), who are tied for fifth in the conference, are 0-4 on the road this year. The RedHawks (5-4, 4-1 MAC), who are in a four-way tie for first place, are 3-1 on their home field in 2025.

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Kickoff from Yager Stadium in Oxford, Ohio, is at 7 p.m. ET. Miami leads the all-time series 29-24-1. The Rockets are 4.5-point favorites in the latest Toledo vs. Miami odds, while the over/under for total points scored is 45.5 via SportsLine consensus. 

Before making any Toledo vs. Miami picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks. Anyone following could have seen impressive returns.

The model has simulated Toledo vs. Miami (Ohio) 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits over 60% of simulations.

So who wins Toledo vs. Miami, and which side of the spread hits over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

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