Steelers vs. Colts: 2022 Week 12 Monday Night Football proven expert predictions including model simulation, DFS picks, best bets

Two teams on the outskirts of the AFC playoff picture square off on Monday night as the Indianapolis Colts play host to the Pittsburgh Steelers at Lucas Oil Stadium. Indianapolis is 4-6-1 and enters off a 17-16 home loss to the NFL's top team, Philadelphia, while Pittsburgh, 3-7, lost to Cincinnati in a high-scoring game last week, 37-30. The Steelers won the last matchup between these two teams, 28-24, in December 2020. 

The Colts are favored by 2.5 in the latest Indianapolis vs. Pittsburgh odds from Caesars Sportsbook and the over/under is set at 39.5. Indianapolis is 5-6 against the spread, while Pittsburgh is 4-5-1 ATS in 2022. Kickoff is scheduled for 8:15 p.m. ET.

Now, our experts and model have dissected the Colts vs. Steelers game and revealed their best bets, props, DFS picks, and more. Join SportsLine here to see what all our experts have to say about this crucial Monday Night Football game! Use promo code MONTH to get one month free!

Find each of our individual previews here:

SportsLine's simulation model thinks the Colts are the top play tonight and has a slight lean on the total.

The SportsLine model has three over plays related to the Pittsburgh offense and a surprising touchdown scorer for Indianapolis.

NFL expert R.J. White praises the progress of the Pittsburgh offense and makes a spread pick on tonight's game.

DFS millionaire Mike McClure favors two Steelers skill position players among his top DFS plays for tonight's game.

DFS expert Jimmie Kaylor is stacking his lineups with a running back and wide receiver from each team.

NFL Insider Jason La Canfora is betting on Kenny Pickett to have a nice game and a potential Steelers upset.

Make your own Week 12 MNF parlay using SportsLine's expert picks! Use promo code MONTH to get your first month of SportsLine for free!

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