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    San Diego State vs. Arizona odds, line: Advanced computer college football model reveals picks for Saturday's matchup

    SportsLine's projection model has generated selections for the contest between the Aztecs and Wildcats
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    The San Diego State Aztecs christen their new home when they host the Arizona Wildcats in the season opener for both teams on Saturday. San Diego State will be hosting its first game at Snapdragon Stadium after calling Dignity Health Sports Park in Carson, California home for the last two campaigns. The Aztecs finished first in the West Division of the Mountain West Conference last season and set a school record for wins with a 12-2 overall record. Arizona is coming off a dismal 1-11 campaign in which it was last in the South Division of the Pac-12.

    Kickoff is set for 3:30 p.m. ET on CBS. The Aztecs are 6-point favorites in the latest San Diego State vs. Arizona odds from Caesars Sportsbook, while the over/under for total points scored is 46. (See up-to-date odds for every game this week on our college football odds page.) 

    Saturday's game also will be streamed live on Paramount+ with their MUST-HAVE Premium plan. Sign up now to get a 7-day free trial. A subscription also gives you access to other sports content including the UEFA Champions League and Europa League, NWSL, NFL on CBS, and countless movies and shows. Get it all free for 7 days when you sign up right here.

    Before you make any Arizona vs. San Diego State picks and college football predictions, you NEED to see the predictions from the SportsLine Projection Model.

    The model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It enters Week 1 of the 2022 college football season on a 45-32 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen HUGE returns.

    The model knows San Diego State finished the 2021 season ranked 25th in the nation, marking just the third time in program history it has accomplished the feat. The Aztecs are 53-41-5 all-time in season openers, including 45-16-4 at home. San Diego State enters with a seven-game winning streak in home season openers.

    The model also knows Arizona suffered a 38-14 loss against San Diego State last season but owns a 10-6 record in the all-time series. The Wildcats have won back-to-back road meetings with the Aztecs since suffering a 42-10 setback at San Diego State in 1979. Arizona has lost 11 consecutive away games since posting a 35-30 victory at Colorado on Oct. 5, 2019.

    Now, the model has set its sights on San Diego State vs. Arizona. We can tell you it is leaning Over the total, and it also says one side of the spread hits in well over 70% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

    Who wins Arizona vs. San Diego State? And which side of the spread hits in well over 70% of simulations? ... Join SportsLine right now to find out which side of the San Diego State vs. Arizona spread you should be all over Saturday, all from the model on a roll on college football picks!

    GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!

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    SportsLine Staff

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