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Pirates vs. Brewers odds, line, start time, picks, best bets for August 13 matchup from proven model

SportsLine's projection model, which is on a 31-23 roll on top-rated MLB money-line picks, has locked in its MLB picks for the Pittsburgh vs. Milwaukee matchup on Wednesday

ByPublished: Aug 13, 2025 2:58AM UTC . 2 min read

The Milwaukee Brewers look to win their 12th game in a row when they battle the Pittsburgh Pirates in the last of a six-game homestand. The Pirates (51-70), who have lost four in a row, are now just 17-41 away from home this season. The Brewers (75-44), who lead the National League Central with the best record in MLB, are 41-20 on their home field.

First pitch from American Family Field in Milwaukee is set for 2:10 p.m. ET. The Brewers have won five of the past six meetings with the Pirates. Milwaukee is a -192 favorite on the money line (risk $192 to win $100) in the latest Pirates vs. Brewers odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over-under, is 7.5 in the latest MLB odds. 

Before you make any Pirates vs. Brewers picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 21 of the 2025 MLB season a profitable 31-23 on top-rated MLB money-line picks. It has excelled making home run prop picks this season, returning nearly 60 units of profit. Anybody following could have seen strong returns!

The model has simulated Pirates vs. Brewers 10,000 times and the results are in. We can tell you the model is going Under on the run total, and it also says one side of the money line has all the value!

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Daniel Kohn

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