Oregon vs. USC odds, line: Advanced computer model reveals picks for Friday's Pac-12 Championship Game matchup

The Oregon Ducks will look to earn their second consecutive Pac-12 Championship Game win when they take on the No. 13 USC Trojans on Friday. Kickoff from the Los Angeles Coliseum is set for 8 p.m. ET. The Trojans are three-point favorites in the latest Oregon vs. USC odds from William Hill Sportsbook, while the over-under is 65.5 (For the latest college football picks for all of this week's games, head over to our college football odds page).

Before making any Oregon vs. USC selections, you MUST check out the FBS college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It is also a sizzling 54-34 on all top-rated picks through 15 weeks of the 2020 college football season, returning over $600. Anyone who has followed it has seen HUGE returns.

Now, it has broken down Oregon vs. USC , and it is leaning Under the total. It also says one side of the spread is cashing in well over 50 percent of simulations! You ABSOLUTELY have to see it before locking in any FBS college football picks of your own.

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