Oregon vs. Missouri line, picks: Advanced computer model reveals picks for big college basketball battle

It's a showdown of two of college basketball's best teams Wednesday when the No. 21 Oregon Ducks face the Missouri Tigers at the CHI Health Center in Omaha, Neb. Tip-off is set for 9 p.m. ET. The Ducks are 4-point favorites in the latest Oregon vs. Missouri college basketball odds from William Hill Sportsbook, while the over-under is 138.5 (For the latest college basketball lines on all of the games, visit our college basketball odds page).

Before making any Missouri vs. Oregon picks, you MUST check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of almost $2,600 for $100 players on its top-rated college basketball picks against the spread. It's also off to a fast start in the 2020-21 season, going 4-1 on its top-rated picks and returning over $300. Anyone who has followed it has seen HUGE returns.

Now, it has broken down Oregon vs. Missouri, and it is leaning Over the total. It also says one side of the spread is cashing in well over 50 percent of simulations! You ABSOLUTELY have to see it before locking in any NCAA college basketball picks of your own.

Who wins Oregon vs. Missouri on Wednesday? And which side of the spread is hitting well over 50 percent of the time? ... Join SportsLine right now to see which side of the Oregon vs. Missouri spread to back Wednesday, all from the advanced model up more than $2,600 on top-rated picks over the past four years!