The eighth-ranked Florida State Seminoles will look to remain undefeated when they take on the Virginia Cavaliers in an Atlantic Coast Conference matchup. The Seminoles (3-0), who are opening their conference slate, were 0-4 on the road last year. The Cavaliers (3-1, 1-0 ACC), who have won two in a row, were 2-4 on their home field in 2024.

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Kickoff from Scott Stadium in Charlottesville, Va., is at 7 p.m. ET. Florida State leads the all-time series 15-4, but Virginia has won two of the last three meetings. The Seminoles are 7-point favorites in the latest Florida State vs. Virginia odds, while the over/under for total points scored is 60.5 via SportsLine consensus. 

Before making any Florida State vs. Virginia picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

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The model has simulated Florida State vs. Virginia 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits in well over 50% of simulations!

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