Through the the first seven weeks of the NFL season, only two teams have suffered only one loss, the 6-1 Indianapolis Colts and the 4-1-1 Green Bay Packers. Who would've guessed that the Daniel Jones-led Colts would rank first in the NFL in points scored (33.1) and second in yards per game (380.3)? It's likely that Indianapolis will be favored in at least six of their final 10 games, if not more, and are the overwhelming favorite to win the AFC South title at -280 odds.

This week, they face the 1-6 Tennessee Titans, fresh off a 31-13 drubbing at home by former Titans-coach Mike Vrabel's New England Patriots. The Colts are the largest point spread favorites this week, giving 14.5 points to the Titans with the over/under at 47.5 points, making Indy just one of two teams that are double-digit favorites. Can Indianapolis avoid a shocking upset and improve to 7-1, with an inside track at home-field advantage in the AFC playoffs? 

The next biggest NFL line has the Chiefs as 12.5-point favorites over Washington, who won't have Jayden Daniels (hamstring). The Commanders face an uphill battle, but they will welcome back both Deebo Samuel and Terry McLaurin.

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With 13 games on the slate for Week 8 of the 2025 NFL season, this week's results could go a long way when determining several teams' short-and-long term futures. Now SportsLine expert Eric Cohen has made his exact score predictions for all 13 games. Before you lock in any NFL picks, make sure you see what Cohen has to say. 

A SportsLine expert and host, Cohen is evaluating the entire Week 8 NFL slate and delivers score predictions and logic for each matchup. After a 10-5 record in Week 7, Cohen is now 70-37-1 (65%) in 2025 following a 190-95 record (69%) in 2024-25 and has been profitable for bettors. 

We can tell you that Cohen likes Eagles (-7.5, 43.5) to beat the Giants in a revenge game from Week 6 at 1 p.m. ET on Sunday. 

"It's inexplicable how the Giants gave up 33 points in the fourth quarter to lose to Denver last week. One of the most improbable NFL results you'll ever see. How their defensive coordinator still has a job is beyond me. While they crushed Philadelphia two weeks ago on Thursday night, look for the Eagles to exact some revenge in Week 8. Though Saquon Barkley has looked like a shell of himself this season, the passing game is showing signs of life with Jalen Hurts and Devonta Smith having big games in Week 7. Look for them to cover the touchdown spread on Sunday. Eagles 28, Giants 18"

In addition, Cohen is picking a high-scoring thriller with 58 total points in Week 8! Nailing this result is key to making profitable Week 8 NFL picks. You ABSOLUTELY NEED to see which game this is before locking in any Week 8 NFL score predictions!

Who wins every Week 8 NFL game, and which game is a must bet for the over on Sunday? ... Join SportsLine now to get Eric Cohen's Week 8 NFL score predictions and find out today!

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