NFL picks: 49ers among expert's best underdog spread bets for Week 8

The NFL season rolls along into Week 8 this weekend, and there's no shortage of spread picks to be made by interested bettors. NFL betting expert Mike Tierney, who is 22-13 (+751) over his last 35 NFL picks, has issued three expert against-the-spread picks for Sunday's slate. You need to see what he has to say before making any NFL spread bets of your own for Week 8.

So what are Mike Tierney's best bets for Week 8 of the 2025 NFL season? Join SportsLine right now to see picks from an expert who is 22-13 over his last 35 NFL picks this season!