NFL DFS, Week 6: Chiefs vs. Lions optimal FanDuel, DraftKings lineups for Sunday Night Football from a daily Fantasy pro

The Kansas City Chiefs host the Detroit Lions on Sunday Night Football in Week 6. Kickoff at GEHA Field at Arrowhead Stadium is scheduled for 8:20 p.m. ET. The NFL DFS player pool is headlined by Patrick Mahomes, Travis Kelce, Xavier Worthy, Jared Goff, Jahmyr Gibbs, and Amon-Ra St. Brown, who were among the top fantasy performers in the NFL in 2025. Should you target Mahomes and Kelce, or Goff and Gibbs when making NFL DFS picks or building NFL DFS stacks? The likes of Jameson Williams, Kareem Hunt, and Hollywood Brown also loom as potential SNF DFS sleeper picks.

Before setting your NFL DFS lineups on sites like DraftKings and FanDuel, you NEED to see what Mike McClure has to say.

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings, including. In 2023, he finished tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him is way up!

Now, McClure has turned his attention to Chiefs vs. Lions on Sunday Night Football and locked in his top daily Fantasy football picks. 

We can tell you one of McClure's top NFL DFS picks for Sunday Night Football is Chiefs quarterback Patrick Mahomes. Part of McClure's optimal NFL DFS strategy also includes rostering Lions running back Jahmyr Gibbs.

McClure is also targeting a player who could go off for MASSIVE numbers for Sunday Night Football! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NFL DFS picks for Lions vs. Chiefs? And which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!