NFL DFS, Week 18 2025: Top FanDuel, DraftKings picks, Saturday lineups from a daily Fantasy pro

The Week 18 NFL schedule kicks off Saturday with a two-game slate of Bucs vs. Panthers and 49ers vs. Seahawks, and a player pool that features options such as Bryce Young, Baker Mayfield, Brock Purdy, Christian McCaffrey, Sam Darnold and Jaxon Smith-Njigba. Both games have major playoff implications, so daily Fantasy interest will be substantial as well. 

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Before making any NFL DFS picks for Saturday on sites like DraftKings and FanDuel, you NEED to hear what SportsLine daily Fantasy expert Mike McClure has to say.

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings, including. In 2023, he finished tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him is way up!

One of McClure's top NFL DFS picks for Week 18 Saturday is Smith-Njigba. He's also building around Bucs receiver Mike Evans, who has scored in two of his three games since returning from a collarbone injury on Dec. 11. 

McClure is also targeting an overlooked value player who could go off for MASSIVE numbers on Saturday! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who they are before locking in any lineups.

What are the top NFL DFS picks, and which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW.