NFL DFS, Week 16: Seahawks vs. Rams optimal FanDuel, DraftKings lineups for 'Thursday Night Football' from a daily Fantasy pro

Week 16 begins with a 'Thursday Night Football' divisional matchup between the Los Angeles Rams and Seattle Seahawks at 8:15 p.m. ET. The likes of Matthew Stafford, Puka Nacua and Jaxon Smith-Njigba are some of the top NFL DFS picks, but any winning daily Fantasy football strategy needs to include low-cost options. Thus, players like Sam Darnold, Zach Charbonnet, Blake Corum and Cooper Kupp loom as potential NFL DFS sleepers. Additionally, Davante Adams (hamstring) is not expected to suit up for 'Thursday Night Football'.

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One can't dismiss the defenses when it comes to scouring the NFL DFS player pool, as both Seattle and Los Angeles rank in the top three in scoring defense. Before setting your NFL DFS lineups on sites like DraftKings and FanDuel, you NEED to see what Mike McClure has to say.

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings, including. In 2023, he finished tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him could be way up!

Now, McClure has turned his attention to 'Thursday Night Football' and locked in his top daily Fantasy football picks. 

One of McClure's top NFL DFS picks for Thursday Night Football is Rams receiver Puka Nacua. Part of his optimal NFL DFS strategy includes rostering Seahawks tight end AJ Barner, who was heavily featured in Week 11 versus the Rams. He had season highs in targets (11) and receptions (10), while his 70 receiving yards were one shy of matching his career high of 71.

McClure is also targeting a player who could go off for MASSIVE numbers for Thursday Night Football! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NFL DFS picks for Thursday, and which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!

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