NFL DFS picks, 2025 Hall of Fame Game: Lions vs. Chargers daily Fantasy lineup advice from top NFL expert

The NFL preseason kicks off with a matchup between the Detroit Lions and Los Angeles Chargers in the 2025 NFL Hall of Fame Game on Thursday at 8 p.m. ET. Established starters rarely suit up in the Hall of Fame Game, making it imperative to hit on players in the NFL DFS player pool who may be listed near the bottom of their respective team's depth chart. Every player in the NFL DFS player pool is priced at $11,400 on DraftKings and $12,000 on FanDuel. 

Before locking in any NFL DFS lineups for Lions vs. Chargers in the 2025 Hall of Fame Game on sites like DraftKings and FanDuel, you NEED to see what SportsLine's NFL R.J. White has to say.

White is an elite NFL handicapper who has cashed twice in the world's most prestigious handicapping tournament, the Westgate Las Vegas SuperContest. He's also SportsLine's No. 1 all-time NFL ATS expert. In addition, he serves as the CBS's Fantasy editor, making him the ideal expert to dig deep on these rosters and make NFL DFS picks. 

Now, White has turned his attention to the 2025 NFL Hall of Fame Game matchup of Detroit vs. Los Angeles and locked in his top daily Fantasy football picks.

One of White's top NFL DFS picks for the Hall of Fame Game 2025, where every player on DraftKings is priced at $11,400 and $12,000 on FanDuel, is Chargers quarterback Trey Lance, who will start for Los Angeles. He also loves Lions quarterback Hendon Hooker, who is entering just his second full healthy season after missing most of 2023 (ACL).

White is also targeting another under-the-radar player for Thursday's matchup who could post HUGE numbers and carry your lineups to victory! His NFL DFS picks could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups!

What are the top NFL DFS picks for the 2025 NFL Hall of Fame Game, and which player is a MUST-ROSTER? ... Join SportsLine now to see NFL expert R.J. White's top picks and player pools for FanDuel and DraftKings, all from an elite NFL expert!