The 2025 NFL season continues Sunday with 12 games, but only 10 will be included on the main slate for many DFS sites since there's an early game in London and 'Sunday Night Football' in the evening. The Week 6 NFL schedule is headlined by 49ers vs. Buccaneers and Jaguars vs. Seahawks, but daily Fantasy players will also have a close eye on Cowboys vs. Panthers, which has the highest over/under on the slate at 49.5 and features potential NFL DFS picks such as Dak Prescott, Bryce Young, Javonte Williams, George Pickens, and Tetairoa McMillan.

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Before making any Week 6 NFL DFS picks on sites like DraftKings and FanDuel, you NEED to hear what SportsLine daily Fantasy expert Mike McClure has to say.

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings, including. In 2023, he finished tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him is way up!

We can tell you one of McClure's top NFL DFS picks for Sunday is Rams wide receiver Puka Nacua at $8,700 on DraftKings and $9,800 on FanDuel. Part of McClure's optimal NFL DFS strategy also includes rostering Cowboys tight end Jake Ferguson at $5,300 on DraftKings and $7,000 on FanDuel.

McClure is also targeting an overlooked value player who could go off for MASSIVE numbers on Sunday! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who they are before locking in any lineups.

What are the top NFL DFS picks for Sunday, and which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW.