NBA DFS, 2026: Top FanDuel, DraftKings picks, lineups, advice for Wednesday, Jan. 21 from daily Fantasy pro

The Wednesday NBA schedule has a seven-game slate, with several star players available for NBA DFS lineups. The likes of Jalen Brunson, LaMelo Ball, Karl-Anthony Towns and Jaylen Brown highlight those available in the NBA DFS player pool. Meanwhile, Cade Cunningham (illness) and Zion Williamson (illness) are among those listed as questionable, so you'll want to monitor their statuses before inserting them into daily Fantasy basketball lineups.

Before making any NBA DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any NBA DFS player.

For Wednesday, one of McClure's top NBA DFS picks is Grizzlies point guard Ja Morant ($7,700 on DraftKings and $7,900 on FanDuel). He's also building around Hornets small forward Brandon Miller ($7,000 on DraftKings and $7,500 on FanDuel), as the former No. 2 overall pick has scored 23-plus points in three straight games.

McClure is also targeting a player who could go off for massive numbers on Wednesday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top NBA DFS picks for Wednesday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NBA DFS!