NBA DFS, 2026: Top FanDuel, DraftKings picks, lineups, advice for Wednesday, Jan. 14 from a daily Fantasy pro

The 2025-26 NBA schedule features a seven-game slate for Wednesday, which begins at 7 p.m. ET. James Harden, Donovan Mitchell, Jalen Brunson and Scottie Barnes are some of the top NBA DFS picks available for daily Fantasy basketball lineups. Meanwhile, the likes of Kawhi Leonard (ankle) and Lauri Markkanen (illness) are both listed as questionable, so you'll want to monitor their statuses before making them a part of your NBA DFS strategy.

Before making any NBA DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with more than $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only at SportsLine. 

For this slate, one of McClure's top NBA DFS picks is Bulls shooting guard Coby White at $5,800 on DraftKings and $6,500 on FanDuel. He's also building around Jazz point guard Keyonte George ($8,200 on DraftKings, $8,400 on FanDuel), who is in the midst of a breakout season with averages of 23.8 points, 6.9 assists and 4.2 rebounds. The third-year player is one of six players averaging at least 23 points and 6 assists per game.

McClure is also targeting a player who could go off for massive numbers on Wednesday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top NBA DFS picks for Wednesday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks and player pools for FanDuel and DraftKings, and cash in BIG on NBA DFS!