NBA DFS, 2026: Top FanDuel, DraftKings picks, lineups, advice for Wednesday, April 29 from a daily Fantasy pro

A trio of Game 5 matchups comprise Wednesday's NBA schedule, and several stars will be in action. Thus, your NBA DFS picks could include the likes of Cade Cunningham, Donovan Mitchell, Alperen Sengun and LeBron James. Meanwhile, Austin Reaves (oblique) and Franz Wagner (calf) are listed as questionable, so you'll want to monitor their statuses before inserting them into daily Fantasy basketball lineups.

Before making any NBA DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any NBA DFS player.

For Wednesday, one of McClure's top NBA DFS picks is Cavs guard Donovan Mitchell ($8,500 on DraftKings, $8,700 on FanDuel). He's also building around Rockets guard Reed Sheppard ($5,400 on DraftKings, $6,200 on FanDuel). Last year's No. 3 overall pick is coming off back-to-back outings with 17 points and 3 steals, while also having 10 total assists over those contests.

McClure is also targeting a player who could go off for massive numbers on Wednesday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top NBA DFS picks for Wednesday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NBA DFS!