The 2025-26 NBA season gets underway on Tuesday, with NBA Opening Night featuring a pair of matchups. Kevin Durant will make his team debut versus Shai Gilgeous-Alexander and the defending champs in Rockets vs. Thunder, followed by Stephen Curry and Luka Doncic facing off in Warriors vs. Lakers. The Lakers won't have LeBron James (sciatica) as he aims for a return in a few weeks. NBA DFS lineups figure to revolve around some of those big names, but which underrated values can you utilize in NBA daily Fantasy for Opening Night 2025?

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Before making your NBA DFS picks on sites like DraftKings and FanDuel for Tuesday, Oct. 21, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any NBA DFS player. 

For Tuesday, one of McClure's top NBA DFS picks is Lakers point guard Luka Doncic, who is listed at $11,000 on DraftKings and $11,700 on FanDuel. Another part of McClure's optimal NBA DFS strategy includes rostering Thunder center Isaiah Hartenstein ($5,400 on DraftKings and $5,800 on FanDuel). In his first year in OKC, Hartenstein posted career highs across the board. He averaged 11.2 points, 10.7 rebounds, 3.8 assists and 1.1 blocks while knocking down 58.1% of his field goal attempts.

McClure is also targeting a player who could go off for massive numbers on Tuesday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top NBA DFS picks for Tuesday? And which player is a must-roster? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NBA DFS!

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