NBA DFS, 2025: Top FanDuel, DraftKings picks, lineups, advice for Wednesday, October 29 from a daily Fantasy pro

The 2025-26 NBA season rolls into its second week of action, with Wednesday, October 29 having a 10-game slate. Thus, there's a sizeable NBA DFS player pool with such stars as Ja Morant, Nikola Jokic, Kevin Durant and Cade Cunningham. Who should you construct your daily Fantasy basketball strategy around, and which under-the-radar options should slot into your NBA DFS lineups?

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1! JOIN NOW. 

Before making your NBA DFS picks on sites like DraftKings and FanDuel for Wednesday, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any NBA DFS player.

For Wednesday, one of McClure's top NBA DFS picks is Nuggets center Nikola Jokic at $12,100 on FanDuel and $11,500 on DraftKings. He's also building around Pacers power forward Pascal Siakam ($8,400 on DraftKings, $9,200 on FanDuel), who has stepped up in the absence of Tyrese Haliburton. Siakam is averaging career highs in points (26), rebounds (10.3) assists (6) and steals (1.3).

McClure is also targeting a player who could go off for massive numbers on Wednesday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top NBA DFS picks for Wednesday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NBA DFS!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1! JOIN NOW.