NBA DFS, 2025: Top FanDuel, DraftKings picks, lineups, advice for Wednesday, Dec. 17 from a daily Fantasy pro

After a one-game slate on Tuesday with the NBA Cup Championship, the Wednesday NBA DFS player pool is slightly bigger with two games on the docket. Bulls vs. Cavaliers and Grizzlies vs. Timberwolves, both at 8 p.m. ET, mean the likes of Donovan Mitchell, Josh Giddey and Jaren Jackson Jr. are some of the biggest names available as NBA DFS picks. Meanwhile, Ja Morant (ankle) and Anthony Edwards (foot) are questionable, so you'll want to monitor their statuses before inserting them into your daily Fantasy basketball lineups.

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Before making any NBA DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any NBA DFS player.

For Wednesday, one of McClure's top NBA DFS picks is Cavs shooting guard Donovan Mitchell ($9,800 on DraftKings and $9,700 on FanDuel). He's also building around Grizzlies PF/C Santi Aldama ($6,400 on DraftKings and $6,500 on FanDuel), who has started the last two games with Zach Edey (ankle) injured. Aldama has scored 22 points in two of his last three games, with 7 rebounds in both of those outings as well.

McClure is also targeting a player who could go off for massive numbers on Wednesday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top NBA DFS picks for Wednesday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NBA DFS!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1! JOIN NOW.