NBA DFS, 2025: Top FanDuel, DraftKings picks, lineups, advice for Friday, Nov. 21 from a daily Fantasy pro

The NBA features a nine-game NBA Cup slate on Friday, providing aa ample NBA DFS player pool. Stars like Donovan Mitchell, Jaylen Brown, Nikola Jokic, Kevin Durant and Steph Curry will be in action, while several others are sidelined indefinitely, including Andrew Wiggins (hip), Tyler Herro (ankle), Kyrie Irving (knee) and Anthony Davis (calf). What combination of highly-priced superstars and economical role players should comprise your daily Fantasy basketball strategy?

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Before making any NBA DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any NBA DFS player.

For Friday, one of McClure's top NBA DFS picks is Cavaliers forward Evan Mobley at $7,900 on DraftKings and $8,300 on FanDuel. He's also rostering Heat forward Jaime Jaquez ($7,000 on DraftKings and $6,800 on FanDuel), who is coming off a 12-point, seven-assist and five-rebound performance in a 110-96 win over Golden State on Wednesday. Jaquez has scored in double figures in each of the last eight games and in 13 of 15 this season.

McClure is also targeting a player who could go off for massive numbers on Friday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top NBA DFS picks for Friday? And which player is a must-roster? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NBA DFS!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1! JOIN NOW.