loading...
League Logo
NFL
League Logo
NFL
League Logo
CFB
League Logo
NBA
League Logo
CBB
League Logo
NHL
All
  • Loading...
loading...

NBA DFS, 2025: Top FanDuel, DraftKings picks, lineups, advice for Friday, Nov. 21 from a daily Fantasy pro

DFS millionaire Mike McClure shares his top NBA DFS lineups for Friday, Nov. 21

By@Mike5754Updated: Nov 21, 2025 11:27PM UTC . 2 min read

The NBA features a nine-game NBA Cup slate on Friday, providing aa ample NBA DFS player pool. Stars like Donovan Mitchell, Jaylen Brown, Nikola Jokic, Kevin Durant and Steph Curry will be in action, while several others are sidelined indefinitely, including Andrew Wiggins (hip), Tyler Herro (ankle), Kyrie Irving (knee) and Anthony Davis (calf). What combination of highly-priced superstars and economical role players should comprise your daily Fantasy basketball strategy?

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1! JOIN NOW. 

Before making any NBA DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any NBA DFS player.

For Friday, one of McClure's top NBA DFS picks is Cavaliers forward Evan Mobley at $7,900 on DraftKings and $8,300 on FanDuel. He's also rostering Heat forward Jaime Jaquez ($7,000 on DraftKings and $6,800 on FanDuel), who is coming off a 12-point, seven-assist and five-rebound performance in a 110-96 win over Golden State on Wednesday. Jaquez has scored in double figures in each of the last eight games and in 13 of 15 this season.

McClure is also targeting a player who could go off for massive numbers on Friday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1! JOIN NOW. 

GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!

JOIN NOW
Avatar
Mike McClure
FOLLOW
Share This Story
© 2025 CBS INTERACTIVE INC. ALL RIGHTS RESERVED. SportsLine and SportsLine PRO are registered trademarks of SportsLine.com, Inc.FANS ONLY
In partnership with...247 Sports

FOLLOW US:

The content on this site is for entertainment purposes only and SportsLine makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. There is no gambling offered on this site. This site contains commercial content and SportsLine may be compensated for the links provided on this site.