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NBA DFS, 2025: Top FanDuel, DraftKings picks, lineups, advice for Friday, Dec. 5 from a daily Fantasy pro

DFS millionaire Mike McClure shares his top NBA DFS lineups today

By@Mike5754Updated: Dec 05, 2025 5:14PM UTC . 2 min read

There is a 12-game NBA regular season slate on Friday, which begins at 7 p.m. ET and has the last tip at 9:30 p.m. ET. Josh Giddey, Tyrese Maxey, Cade Cunningham, Nikola Jokic and Jalen Johnson are among the most expensive options in the NBA DFS player pool. There are a number of injured players, including Zach Collins (wrist) and Coby White (calf), who are listed as questionable, and Jalen Smith (hamstring), who is doubtful. Ja Morant (calf) and Giannis Antetokounmpo (calf) are listed as out.

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Before making any NBA DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any NBA DFS player.

For Friday, one of McClure's top NBA DFS picks is Bucks point guard Kevin Porter Jr. at $6,600 on DraftKings and $6,800 on FanDuel. He's also building around Bucks power forward/center Bobby Portis ($5,400 on DraftKings, $5,500 on FanDuel), who is coming off a near double-double with 13 points, nine rebounds and five assists in the 113-109 win over Detroit on Wednesday. Portis will be leaned on to do more offensively with Giannis Antetokounmpo (calf) out, and he's averaging 11.1 points, 1.3 assists and 5.7 rebounds in 23 games this season.

McClure is also targeting a player who could go off for massive numbers on Friday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

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