The first and final first pitches of the Wednesday MLB schedule are more than 10 hours apart as Wednesday features possibly the most jam-packed day of the 2025 MLB season. Due to multiple rainouts on Tuesday, the Wednesday MLB schedule opens with a 17-game slate. Some of those could be cancelled again with poor weather in parts of the country, but for daily Fantasy baseball players, there are ample ways to create an MLB DFS strategy with a bevy of slates to choose from. The nightcap closes with the Athletics vs. Dodgers with a 10:10 p.m. ET first pitch after a surprising 11-1 victory for the Athletics in the first game of the series, so should your MLB DFS lineups include Athletics such as Jacob Wilson, Brent Rooker or Miguel Andujar from the MLB DFS player pool?

Before setting your MLB DFS lineups on daily Fantasy sites like DraftKings and FanDuel for Wednesday, May 14, you NEED to see the top MLB DFS picks from Mike McClure. McClure is a daily Fantasy pro with over $2 million in career winnings. 

When it comes to MLB, McClure is at his best. Recognized in the book "Fantasy Football (and Baseball) for Smart People: How to Turn Your Hobby into a Fortune," McClure's proprietary MLB DFS projection model simulates each game 10,000 times, taking factors such as matchups and recent results into account. This allows him to find the best values on every site.

On Tuesday, McClure identified Padres pitcher Dylan Cease as his top starting pitcher for MLB DFS picks on both sites. The result: Cease allowed two runs on five hits with one walk and 10 strikeouts over 6 2/3 innings, returning 27.4 points on DraftKings and 48 points on FanDuel. Anybody who included him in their lineups could have been well on the way to a profitable day!

One of McClure's top MLB DFS picks for Wednesday is Rangers outfielder Wyatt Langford, who is $5,300 on DraftKings and $3,500 on FanDuel for MLB DFS lineups. McClure is also rostering Nationals shortstop CJ Abrams ($4,800 on DraftKings and $3,300 on FanDuel). Abrams hit his fifth home run of the season on Tuesday and he's batting .407 over his last six games. Bryce Elder is starting for the Braves against Washington and Abrams is 3-for-10 in his career against the right-handed pitcher.

McClure is also targeting a player who is set to EXPLODE for huge numbers on Wednesday! The stars are aligning for him to return tournament-winning value, and he comes at a price that won't break the bank. This pick could be the difference between cashing in big or going home with nothing!

What players can you bank on in MLB DFS for Wednesday, and which undervalued player is a MUST-ROSTER?... Join SportsLine now to see DFS pro Mike McClure's top picks and player pools for FanDuel and DraftKings, and cash in BIG on MLB DFS!