The 2025 MLB season continues on Wednesday with a slew of games throughout the day, with the first pitch of the first game set for 12:35 p.m. ET and the final start at 8:40 p.m. ET. Daily Fantasy baseball players have plenty of options for different formats to make MLB DFS picks, and anyone focusing on the night slate has options like Juan Soto, Aaron Judge and Bobby Witt Jr. from the MLB DFS player pool to consider for a Wednesday MLB DFS strategy.

Before setting your MLB DFS lineups on daily Fantasy sites like DraftKings and FanDuel for Wednesday, June 11, you NEED to see the top MLB DFS picks from Mike McClure. McClure is a daily Fantasy pro with over $2 million in career winnings. 

When it comes to MLB, McClure is at his best. Recognized in the book "Fantasy Football (and Baseball) for Smart People: How to Turn Your Hobby into a Fortune," McClure's proprietary MLB DFS projection model simulates each game 10,000 times, taking factors such as matchups and recent results into account. This allows him to find the best values on every site.

On Tuesday, McClure highlighted Giants shortstop Willy Adames as one of his top MLB DFS picks on both sites. The result: Adames went 1-for-3 with a home run, a walk, two RBI and two runs scored, returning 20 points on DraftKings and 28.4 points on FanDuel. Anybody who included him in their lineups could have been well on the way to a profitable day!

One of McClure's top MLB DFS picks for Wednesday is Astros second baseman/outfielder Jose Altuve, who is $4,200 on DraftKings and $2,900 on FanDuel for MLB DFS lineups. McClure is also rostering Giants outfielder Jung Hoo Lee ($5,000 on DraftKings and $3,400 on FanDuel). Lee had a triple and two runs scored against the Rockies on Tuesday, as the Giants are the current team fortunate enough to be matched up against Colorado. The Rockies have allowed nine runs per game over their last three contests and are 3-12 over their last 15 games as their abysmal 2025 MLB season continues. Lee has at least one hit in each of his last four starts, and McClure expects him to take advantage of Colorado pitching on Wednesday. 

McClure is also targeting a player who is set to EXPLODE for huge numbers on Wednesday! The stars are aligning for him to return tournament-winning value, and he comes at a price that won't break the bank. This pick could be the difference between cashing in big or going home with nothing!

What players can you bank on in MLB DFS for Wednesday, and which undervalued player is a MUST-ROSTER?... Join SportsLine now to see DFS pro Mike McClure's top picks and player pools for FanDuel and DraftKings, and cash in BIG on MLB DFS!