MLB DFS, 2026: Top FanDuel, DraftKings picks, lineups, advice for Wednesday, April 29, from a daily Fantasy pro

Wednesday is getaway day for many teams as there are just eight games in the evening, making for a rather limited MLB DFS player pool. With that being said, high-quality options are still available for daily Fantasy baseball lineups such as Bryce Harper, Jordan Walker and Corbin Carroll. As for options on the mounds, there's the likes of Logan Webb, Cristopher Sanchez and Eduardo Rodriguez. Who should factor into your Wednesday MLB DFS strategy?

Before making any MLB DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best MLB DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any MLB DFS player.

For Wednesday, one of McClure's top MLB DFS picks is Astros OF/DH Yordan Alvarez ($6,500 on DraftKings, $4,400 on FanDuel). He's also rostering Reds 2B/SS Matt McClain ($3,200 on DraftKings, $2,900 on FanDuel). McClain's bat is heating up as of late as he has a .900 OPS over his last seven games.

McClure is also targeting a player who could go off for massive numbers on Wednesday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top MLB DFS picks for Wednesday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on MLB DFS!