MLB DFS, 2026: Top FanDuel, DraftKings picks, lineups, advice for Thursday, March 26, from a daily Fantasy pro

An 11-game slate highlights Thursday's MLB Opening Day schedule, which begins at 1:15 p.m. ET, with the last first pitch coming at 10:10 p.m. ET. Among the top options in the MLB DFS player pool include Freddie Freeman, Trea Turner, Shohei Ohtani, Pete Alonso, Cal Raleigh, Julio Rodriguez, Kyle Schwarber and Paul Skenes. Among those starting the season on the injured list include Blake Snell (shoulder), Spencer Strider (oblique), Merrill Kelly (back), Tommy Edman (ankle), Anthony Rendon (hip) and Jackson Holliday (hand).

Before making any MLB DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best MLB DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any MLB DFS player.

For Thursday, one of McClure's top MLB DFS picks is Tampa Bay first baseman Yandy Diaz ($4,400 DraftKings, $3,100 FanDuel). He's also building around Tampa Bay third baseman Junior Caminero ($5,800 DraftKings, $3,800 FanDuel). Last season, in 154 games, Caminero hit .264 with a team-high 45 home runs, 28 doubles and 110 RBI. He finished the season on a tear, going 8-for-19 with a homer, two RBI and three walks over the final five games.

McClure is also targeting a player who could go off for massive numbers on Thursday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top MLB DFS picks for Thursday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on MLB DFS!