MLB DFS, 2026: Top FanDuel, DraftKings picks, lineups, advice for Friday, April 3, from a daily Fantasy pro

A full 15-game MLB slate will be featured on Friday, beginning at 1:05 p.m. ET, with the last first pitch set for 10:15 p.m. ET. Among the top options in the MLB DFS player pool include Dylan Cease, Aaron Nola, Framber Valdez, Shohei Ohtani, Brady Singer, Kyle Schwarber, Aaron Judge, Kyle Tucker, Vladimir Guerrero Jr., Freddie Freeman, Corey Seager, Max Muncy, Gunnar Henderson, Mookie Betts, Pete Alonso and George Springer. Among those on the injured list include Lourdes Gurriel Jr. (knee), Sean Murphy (hip), Heston Kierstad (hamstring), Jackson Holiday (finger), Jackson Chourio (hand), Andrew Vaughn (hand), Anthony Volpe (shoulder), Seiya Suzuki (knee), Hunter Greene (elbow) and Spencer Strider (oblique).

Before making any MLB DFS picks on sites like DraftKings and FanDuel for this slate, you need to see what Mike McClure has to say.

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best MLB DFS values and create optimal lineups that he shares only at SportsLine. They're a must-see for any MLB DFS player.

For Friday, one of McClure's top MLB DFS picks is Philadelphia outfielder Kyle Schwarber ($6,200 DraftKings). He's also building around Philadelphia first baseman Bryce Harper ($5,000 DraftKings). Last season, in 132 games, Harper hit .261 with 27 home runs, 32 doubles and 75 RBI. He has one homer and three RBI to start the season.

McClure is also targeting a player who could go off for massive numbers on Friday! This pick could be the difference between winning your tournaments and cash games or going home with nothing. You absolutely need to see who it is before locking in any lineups.

What are the top MLB DFS picks for Friday? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on MLB DFS!