WBC welterweight champion Mario Barrios defends his title Saturday against iconic former champion Manny Pacquiao in a 12-round main event. The pay-per-view main card is set for 8 p.m. ET from MGM Grand Garden Arena in Las Vegas.

Barrios is a -275 favorite (risk $275 to win $100), while Pacquiao fetches a price of +210 (risk $100 to win $210) in the latest boxing odds for Manny Pacquiao vs Mario Barrios. The over/under for total rounds completed is 10.5, with the Over favored at -140 and the Under listed at +105. Barrios winning by KO/TKO/DQ is the favored outcome at +135, followed by Barrios winning by any kind of decision (+200).

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Before locking in your Manny Pacquiao vs. Mario Barrios picks, you NEED to see the boxing predictions and betting advice from SportsLine analyst Josh Nagel.

Nagel, who is the combat sports editor for SportsLine, is an experienced and successful boxing analyst. He previously served as SportsLine's main boxing analyst and covered the sport for multiple outlets for more than 20 years. He has recently returned to his role as SportsLine's top boxing analyst, and his recent winners include calling Dimitry Bivol (+110) to pull the slight upset of Artur Beterbiev in their February rematch. In April, he correctly called Jarron Ennis to beat Eimantas Stanionis by KO (+155), while also correctly predicting the Under 10.5 rounds (+165). He also correctly called Jake Paul by decision (-110) against Julio Cesar Chavez Jr. in June. He kept his hot streak going by recommending Katie Taylor (+170) against Amanda Serrano in their trilogy showdown just last week. Anyone who has followed Nagel's combat sports picks this year could already be up more than $1,500!

Now, with Manny Pacquiao vs. Mario Barrios approaching, Nagel has studied the boxing match from every angle and released confident picks on the money line, total rounds completed and a method-of-victory prop. 

We can tell you he likes the Over on total rounds (9.5), and he's also locked in a confident money-line pick and a method-of-victory prop that returns around +200! You ABSOLUTELY need to see Nagel's picks before making any of your own!

Who wins Manny Pacquiao vs. Mario Barrios, and which method of victory prop presents massive value? ... Join SportsLine here to see which bets you need to make for the fight, all from the accomplished veteran combat sports analyst who has consistently delivered winners!

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