Early Week 12 Fantasy Football waiver wire: Jacoby Brissett keeps dealing, among 30 pickups to consider

We talked about Sean Tucker and Jacoby Brissett being potential waiver options last week, and the former rolled up 140 total yards and three TDs while the latter set the NFL record for completions in a game on Sunday. Tucker might be a popular addition this week coming off his huge performance, but his Fantasy relevance clock is ticking with Bucky Irving slated to see more work in practice this week ahead of a potential return in Week 12.

Brissett is set to get at least a few more games as a starter with Kyler Murray on IR and considering he's had 250+ passing yards and two passing TDs in all five starts, he's going to remain Fantasy relevant for as long as he's on the field. I added him in one league and started him over Bo Nix with the latter's tough matchup in Week 11, and I may just roll with Brissett moving forward.

Now we turn to Week 12, where several injuries have shifted the Fantasy landscape once again. Josh Jacobs and Drake London are set to miss time, while Calvin Ridley returned from one injury to suffer another that will end his season. Jaylen Warren and Kimani Vidal didn't finish their games as well. And that's before we get to quarterback, where Michael Penix may be lost for the season while Aaron Rodgers and Dillon Gabriel could be forced to miss time. None of those quarterbacks are Fantasy relevant on their own, but any change at the position can threaten to have a trickle-down effect on the rest of the skill players on a roster.

That gives us a lot to go over in my full look at the best waiver options for Week 12 as we cover 30 players at quarterback, running back, receiver and tight end to cover in this week's early waiver wire column.

Which running back should be your top target on Week 12 waivers? And which quarterback is worth adding with a priority bid? ... Join SportsLine here to see R.J. White's Week 12 waiver wire for 2025 Fantasy football leagues!