Colorado vs. TCU line, picks: Advanced computer college football model releases prediction, best bets for non-conference season opening matchup

Week 1 will continue on Saturday when the Colorado Buffaloes battle the TCU Horned Frogs in a non-conference matchup at noon ET from Amon G. Carter Stadium in Fort Worth, Texas. The Horned Frogs are 21-point favorites, while the over/under is set at 63.5 (see up-to-date odds for every game this week on our college football odds page) in the latest Colorado vs. TCU odds. 

Before making any Colorado vs. TCU picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows that dating back to 2003, the Horned Frogs have a nine-game winning streak against Pac-12 opponents. TCU is 77-40-9 in season openers and will be led by redshirt sophomore quarterback Chandler Morris. He will be making his second straight season-opening start against Colorado. In last year's 38-13 win in Boulder, Morris left the game in the third quarter due to injury. He had completed 13 of 20 passes for 111 yards, while rushing four times for 18 yards. Saturday will mark his fourth career start.

The model also knows the Buffaloes are building from the ground up behind former NFL superstar and Jackson State coach Deion Sanders. The Buffaloes feature 87 newcomers on their 2023 roster, including 68 scholarship players. Just nine scholarship and 25 overall players return from 2022. Sanders is 27-6 as a collegiate head coach, including a 23-3 record in his final two seasons at Jackson State with two SWAC championships and two appearances in the Celebration Bowl.

Now, it has set its sights on Colorado vs. TCU. We can tell you the model is leaning Under on the point total, and it also says one side of the spread has all the value! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Colorado vs. TCU, and which side of the spread has all the value? ... Join SportsLine right now to find out which side of the Colorado vs. TCU spread you should be all over Saturday, all from the model that's up nearly $2,500 on top-rated CFB spread picks since its inception!