California vs. Southern California odds, line, spread: Proven model reveals college basketball picks, predictions for Jan. 6, 2022

A Pac-12 battle is on tap between the California Golden Bears and the No. 7 Southern California Trojans at 11 p.m. ET on Thursday at Haas Pavilion. California is 9-5 overall and 9-1 at home, while the Trojans are 12-0 overall and 3-0 on the road. USC is ranked first in the Pac-12; California is ranked fourth. 

The Trojans are favored by 5.5 points in the latest California vs. Southern California odds from Caesars Sportsbook, while the over-under is set at 128. Before you make any Southern California vs. California picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated California vs. Southern California 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins California vs. Southern California? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.