Astros vs. Red Sox odds, picks: Advanced computer MLB model reveals picks for Tuesday matchup

The Houston Astros take on the Boston Red Sox at 7:10 p.m. ET on Tuesday. The Red Sox are -130 favorites (risk $130 to win $100) at Caesars Sportsbook for the MLB on TBS tilt, while the Over-Under is set at 8.5 (see up-to-date odds for every game this week on our MLB odds page). 

Before making any Astros vs. Red Sox picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a profitable start to the 2022 season. It's on a 33-25 roll on top-rated MLB money-line picks through six weeks, returning over $300 for $100 players. Anyone following it has seen HUGE returns!

The model knows that the Astros have a rookie sensation in shortstop Jeremy Peña. The 24-year-old is slashing a spectacular .276/.339/.514 entering Tuesday's game, picking up where the recently-departed Carlos Correa left off. The rookie has smashed six homers and tallied 20 RBI. He's second in the league in WAR thanks to his strong bat and impressive defense. Peña has been sidelined the last few days with knee soreness, but was available off the bench on Monday and should provide an immediate lift to the lineup if he plays today.

The model also knows Red Sox third baseman Rafael Devers is leading the league in hits with 47. The former All-Star is hitting a robust .322 -- and he's not even leading his own team in batting average. That honor belongs to shortstop Xander Bogaerts, who's hitting .346. The left side of the Boston infield is an offensive dynamo, and they present a tough task for Astros starter Jose Urquidy. 

Now, it has set its sights on Astros vs. Red Sox. We can tell you the model is leaning over the total, and one side of the money line has ALL the value! You ABSOLUTELY need to see it before locking in any MLB picks.

Will the Astros or Reds Sox come out on top? And which team has ALL the value on the money line? ... Join SportsLine right now to find out which side of the Astros vs. Red Sox matchup you should be all over Tuesday, all from the model on a roll on MLB picks!