The Week 4 college football schedule unfolds over the course of Thursday, Friday and Saturday, and there are three ranked matchups -- Illinois vs. Indiana, Oklahoma vs. Auburn and Texas Tech vs. Utah.

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Among the notable Week 4 college football odds, Utah is -3.5 against Texas Tech, Oklahoma is -6.5 against Auburn and Indiana is -6.5 against Illinois. If looking for large Week 4 college football spreads, Oregon is favored by 34.5 points over Oregon State (see more college football lines right here). 

Before making any Week 4 college football bets, be sure to see what legendary college football handicapper Bruce Marshall has to say. 

For years Vegas-based Marshall was synonymous with The Gold Sheet, the famed sports betting newsletter. He has won various handicapping titles and crushed the 2024 college football season, going 64-43 (plus 16.24 units) at SportsLine! He also enters Week 4 on a 15-6 roll on his official college football spread picks this season.

Now he's studied the Week 4 college football schedule and used his Tech Corner technique to break down every matchup.

One thing we can tell you for Week 4: Marshall likes Tennessee (-39.5) to cover against UAB in a game that also goes Over the total of 69.5.

"The Blazers were 0-5 as an underdog last season before slipping inside 3 TD-line at Navy on September 6. UAB went Over first three this season and are now over 10-2-1 since early 2024. The Vols have covered last four as chalk and last three laying double digits, also over seven straight since late 2024."

Marshall has evaluated every other matchup and he's found a key 8-0 ATS trend you need to know about in Week 4! You ABSOLUTELY need to see who it is before making any college football picks. 

Who should you back in Week 4 of college football, and what alarming trend do you need to know about in the week's biggest game? ... Join SportsLine now to find out, all from the legendary Vegas handicapper who has won multiple handicapping titles and went 64-43 on CFB picks last year!

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