The Week 2 college football schedule kicks off Friday with four games, and then rolls into another intriguing Saturday highlighted largely by non-conference games.

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Among the notable Week 2 college football odds, Oklahoma is -5.5 against Michigan, Iowa State is -3.5 versus Iowa, Ole Miss is -9.5 against Kentucky, NC State is -3 versus Virginia and Virginia Tech is -2.5 against Vanderbilt (see more college football lines right here). 

Before making any Week 2 college football bets, be sure to see what legendary college football handicapper Bruce Marshall has to say. 

For years Vegas-based Marshall was synonymous with The Gold Sheet, the famed sports betting newsletter. He has won various handicapping titles and crushed the 2024 college football season, going 64-43 (plus 16.24 units) at SportsLine!

Now he's studied the Week 2 college football schedule and used his Tech Corner technique to break down every matchup.

One thing we can tell you for Week 2: Marshall likes Ole Miss (-9.5) to cover against Kentucky in a game that goes under the total. "This is a revenge spot for Rebel after being dumped 20-17 by 15-point underdog UK in Oxford last season. Lane Kiffin 7-4-1 vs. spread last 12 away from Vaught-Hemingway."

Marshall has evaluated every other matchup and he's found a key 10-1 ATS trend you need to know about in one of the biggest Week 2 college football matchups! You ABSOLUTELY need to see who it is before making any college football picks. 

Who should you back in Week 2 of college football, and what alarming trend do you need to know about in the week's biggest game? ... Join SportsLine now to find out, all from the legendary Vegas handicapper who has won multiple handicapping titles and went 64-43 on CFB picks last year!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW.