The 2025 Brickyard 400 will crown either Ty Gibbs or Ty Dillon as the inaugural NASCAR In-Season Challenge champion on Sunday. Indianapolis Motor Speedway will host the event at 2 p.m. ET, but there's also a chase for the Cup Series championship that all drivers in the race are a part of. William Byron, who is seeking his second win of the season, is the +450 favorite, according to the latest 2025 Brickyard 400 odds.

He's followed by reigning IMS winner Kyle Larson (+500), Chase Briscoe (+700) and Denny Hamlin (+750). Two-time Brickyard winner, Brad Keselowski, is at +1600 to utilize in 2025 NASCAR at Indianapolis bets, while longshots include both Gibbs (+1600) and Dillon (+50000). Before making any NASCAR at Indianapolis predictions, you NEED to see the latest 2025 Brickyard 400 picks from SportsLine's proven projection model.

Our proven projection model has simulated Sunday's 2025 Brickyard 400 10,000 times and come up with a surprising leaderboard. Developed by daily Fantasy pro and SportsLine predictive data engineer Mike McClure, this proprietary NASCAR prediction model takes into account a slew of factors, including track history and recent results.

McClure's model began the 2025 season by calling Chase Elliott's win in the Cook Out Clash at Bowman Gray for a +300 payout. Then it went on to predict Kyle Larson in Miami (+350), Christopher Bell's NASCAR All-Star Race win (+600), Denny Hamlin's win in Michigan (+650), Shane van Gisbergen's win in Mexico City (+330), Elliott's win in Atlanta (+1500) and van Gisbergen again in Chicago (+150) and Sonoma (+125).

All told, the model has nailed a whopping 26 winners since 2021 and has hit eight winners already in 2025! Anyone who followed its lead on those NASCAR picks could have seen HUGE returns.

Now, the model has dialed in on NASCAR at Brickyard 2025 and released its projections.

For Sunday's 2025 Brickyard 400, we can tell you the model is high on Joey Logano, even though he's a longshot at +2600 in the latest 2025 NASCAR at Indianapolis odds. He's a target for anyone looking for a HUGE payday. It's also revealed a shocking NASCAR prop for Sunday: Christopher Bell finishes top five for a +160 payout. He's a potentially a strong value pick for your Brickyard NASCAR prop bets.

The model is also targeting THREE OTHER drivers with odds of 12-1 or longer to make a serious run at the checkered flag! Anyone who backs these drivers could hit it BIG. You ABSOLUTELY NEED to see who they are before locking in any NASCAR picks.

So who wins the 2025 Brickyard 400, and which EPIC longshots are MUST-BACKS? ... Join SportsLine right now to see the full projected NASCAR at Indianapolis leaderboard, all from the model that's nailed 26 winners!