2021 NCAA Tournament odds, lines: Proven model reveals picks for USC-Kansas second-round showdown

It's a high-profile showdown in the second round when the sixth-seeded Southern Cal Trojans (23-7) take on the No. 3-seeded Kansas Jayhawks (20-8) in the 2021 NCAA Tournament on Monday. Tip-off is set for 9:40 p.m. ET in Indianapolis. The Trojans are one-point favorites in the latest USC vs. Kansas odds at William Hill Sportsbook, and the Over-Under for total points scored is 135 (Check out the latest college basketball lines for all of today's games over at our college basketball odds page). 

Before making any USC vs. Kansas picks, you MUST check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of over $2,500 for $100 players on its top-rated college basketball picks against the spread. It has also returned almost $500 on all top-rated college basketball picks this season. Anyone who has followed it has seen HUGE returns.

Now, it has broken down USC vs. Kansas, and we can tell you the model is leaning Over the total. It also says one side of the spread has all the value. You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins USC vs. Kansas? And which side of the spread has all the value? ... Join SportsLine right now to find out which side of the USC vs. Kansas spread you should be all over Monday, all from the model up more than $2,500 on its top-rated college basketball picks over the past four seasons!