2021 NCAA Tournament Florida State vs. Colorado line, picks: Advanced computer college basketball model releases selections for second round matchup

The Florida State Seminoles and the Colorado Buffaloes square off in the second round of the 2021 NCAA Tournament at 7:45 p.m. ET on Monday. Florida State is favored by 1.5 points at William Hill Sportsbook, while the Over-Under is set at 141 (see up-to-date odds for every game this week on our college basketball odds page). 

Before making any Florida State vs. Colorado picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of over $2,500 for $100 players on its top-rated college basketball picks against the spread. It has also returned almost $500 on all top-rated college basketball picks this season. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on Florida State vs. Colorado. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in almost 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Florida State vs. Colorado? And which side of the spread hits in nearly 60 percent of simulations? ... Join SportsLine right now to find out which side of the Florida State vs. Colorado spread you should be all over Monday, all from the model on a roll on college basketball picks!