I'm jumping on Purdue early at -4.5 Saturday. I like the matchup at home for the Boilermakers. Iowa State is playing its first true road game this season and I worry about their metrics guarding the perimeter, despite facing a soft home schedule so far this year. The Cyclones do have a really good win over St. John's but playing on a neutral court with a few hundred fans and going on the road in front of a raucous crowd isn't the same thing. I think the Boilermakers will make more perimeter shots, avoid turnovers and I give them an edge on the offensive boards. The line may move against me but I'm fine with 4.5. Bet up to 5.5.