The Guardians are 22-9 at home while the Mariners are 17-20 (with a -22 run differential) on the road. Luis Castillo taking the mound for the Mariners means the pitching matchup appears to favor the Mariners, but they've gone 3-4 in his road starts this year. Plus, the Guardians have already knocked him around this year (4/2 in Seattle: 10 hits and 4 runs in 5 2/3 innings). The Guardians have the inconsistent Logan Taylor Allen, but he threw six scoreless innings against the Mariners on April 3 and they have the superior offense and bullpen here.