Xavier vs. Indiana odds, line, spread: Proven model reveals college basketball picks, predictions for Nov. 18, 2022

The Xavier Musketeers will take on the No. 12 Indiana Hoosiers at 6 p.m. ET Friday at Cintas Center. Indiana blew out its first two opponents at home and is now going on the road for the first time this season. The Hoosiers are favored by 2.5 points in the latest Xavier vs. Indiana odds from Caesars Sportsbook, while the over/under is set at 142.5. 

Before you make any Indiana vs. Xavier picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past six-plus years, the proprietary computer model has generated more than $1,200 for $100 players on its top-rated college basketball picks against the spread. Anybody who has followed it has seen profitable returns.

Now, it has simulated Xavier vs. Indiana 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 80% of simulations! You absolutely need to see it before locking in your own picks.

So who wins Xavier vs. Indiana? And which side of the spread hits almost 80% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.