Wisconsin vs. Penn State odds, prediction: 2026 Big Ten Conference men's college basketball picks from proven model

The Wisconsin Badgers will look to extend their winning streak to five games when they take on the Penn State Nittany Lions in a key Big Ten Conference matchup on Thursday night. Wisconsin is coming off a 96-87 win over Rutgers on Saturday, while Penn State dropped a 96-73 decision at Maryland on Sunday. The Badgers (13-5, 5-2 Big Ten), who are looking to reach 20 wins for the fifth consecutive season, are 2-2 on the road this season. The Nittany Lions (9-9, 0-7 Big Ten), who have lost five in a row, are 7-4 on their home floor.

Tip-off from Bryce Jordan Center in State College, Pa., is set for 7 p.m. ET. Wisconsin leads the all-time series 44-13, including a 19-9 edge in games played at State College. Wisconsin is a 5.5-point favorite in the latest Wisconsin vs. Penn State odds from DraftKings Sportsbook, while the over/under for total points scored is 159.5. 

Before making any Wisconsin vs. Penn State picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 12 on a sizzling 10-1 run on top-ranked over/under picks. Anyone following could have seen HUGE returns!

The model has simulated Wisconsin vs. Penn State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in nearly 60% of simulations!

So who wins Wisconsin vs. Penn State, and which side hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!