A pair of Big Ten Conference powerhouses meet when the No. 9 Wisconsin Badgers visit the No. 12 Michigan State Spartans on Christmas Day. Tip-off from the Jack Breslin Student Events Center, is set for 12:30 p.m. ET. Wisconsin is favored by 1.5-points, while the Over-Under is set at 140 in the latest Wisconsin vs. Michigan State odds from William Hill Sportsbook (see up-to-date predictions for every game this week on our college basketball odds page). 

Before making any Michigan State vs. Wisconsin picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of almost $2,600 for $100 players on its top-rated college basketball picks against the spread. It's off to a profitable start in the 2020-21 season, going 12-9 on all its top-rated picks and returning almost $300. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on Wisconsin vs. Michigan State. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Wisconsin vs. Michigan State? And which side of the spread hits in over 50 percent of simulations? ... Join SportsLine right now to find out which side of the Michigan State vs. Wisconsin spread you should be all over on Christmas Day, all from the model on a roll on college basketball picks!