Wisconsin-Milwaukee vs. IU Indianapolis odds, prediction: 2026 Horizon League men's college basketball picks from proven model

Teams looking to turn around their recent fortunes meet when the Wisconsin-Milwaukee Panthers take on the IU Indianapolis Jaguars in Horizon League action on Tuesday. Milwaukee is coming off a 67-62 loss at Northern Kentucky on Saturday, while IU Indianapolis downed Cleveland State 82-74 that same day. The Panthers (9-17, 5-10 Horizon), who have lost four in a row, are 2-11 on the road this season. The Jaguars (7-18, 3-11 Horizon), who have lost nine of 12, are 5-5 on their home floor.

Tip-off from The Jungle in Westfield, Ind., is set for 6:30 p.m. ET. Milwaukee leads the all-time series 11-2, including a 95-83 win on Jan. 11. IU Indianapolis is a 1-point favorite in the latest Milwaukee vs. IU Indianapolis odds from DraftKings Sportsbook, while the over/under for total points scored is 162.5. 

Before making any Milwaukee vs. IU Indianapolis picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 15 on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on an 11-5 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated Milwaukee vs. IU Indianapolis 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits well over 50% of the time!

So who wins Milwaukee vs. IU Indianapolis, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!