White Sox vs. Red Sox odds, lines: Advanced computer MLB model reveals picks for Patriots' Day matchup

The Boston Red Sox resume their tradition of hosting the Patriots' Day game at Fenway Park after last year's contest was cancelled due to the coronavirus pandemic when they conclude their four-game series against the Chicago White Sox on Monday morning. First pitch is scheduled for 11:10 a.m. ET.

Chicago sends Lucas Giolito (1-0, 2.55 ERA) to the mound against fellow right-hander Nathan Eovaldi (2-1, 2.08). Chicago is the -121 favorite (risk $121 to win $100) on the money line at William Hill Sportsbook, while the Over-Under for runs scored is eight in the latest White Sox vs. Red Sox odds (see up-to-date lines for every game on our MLB odds page). 

Before making any White Sox vs. Red Sox picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. It is off to a fast start in 2021, going 15-7 on all top-rated MLB picks through two weeks, returning over $500. Anyone following it has seen HUGE rewards.

Now, it has set its sights on White Sox vs. Red Sox. We can tell you it's leaning Over, but it also says one side of the money line has all the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So who wins White Sox vs. Red Sox? And which side of the money line has all the value? ... Join SportsLine right now to find out which side of the White Sox vs. Red Sox money line you should be all over on Monday, all from the model that was up over $1,400 on MLB picks in 2019!