The Week 6 NFL schedule wraps up with a double-header on 'Monday Night Football'. In the first game, the Atlanta Falcons host the Buffalo Bills at 7:15 p.m. ET. In the second game of the night, the Washington Commanders host the Chicago Bears at 8:15 p.m. ET. Both games carry early leverage -- not just in standings, but in setting momentum for teams trying to be more than pretenders this season. How should you handle betting on Monday Night Football NFL player props? And which NFL prop bets should you target?

With sites like DraftKings, FanDuel, BetMGM, PrizePicks, Underdog Fantasy, Sleeper Fantasy, and more offering picks surrounding Week 6 NFL player props, you'll want to check out the top Week 4 Monday Night Football player props and NFL prop predictions from SportsLine's AI PickBot. 

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each player prop. 

Now, the AI PickBot has scoured the Week 4 NFL player props market and locked in its most confident picks.

After analyzing Monday Night Football props and examining the dozens of NFL player prop markets, the AI PickBot says Bills running back James Cook goes comfortably Over 16.5 rushing attempts, projecting a him to finish with 19.9 carries.

The AI PickBot has also locked in four more 4.5-star prop plays for MNF, including a pair of confident 4.5-star best bets involving Bills quarterback Josh Allen. 

Which NFL prop bets should you target for Monday Night Football in Week 6, and which Josh Allen props are the AI PickBot calling 4.5-star picks? Join SportsLine now to see the top 2025 Week 6 NFL props for Monday Night Football, all from the self-learning SportsLine AI PickBot that's built on cutting-edge technology, and find out!