Virginia vs. Missouri prediction, odds, time: 2025 Gator Bowl picks from proven model

The 2025-26 college football bowl schedule continues on Saturday, Dec. 27, when the Missouri Tigers face the Virginia Cavaliers in the 2025 Gator Bowl. Virginia just missed a spot in the CFP as it lost to Duke in the ACC Championship Game. Mizzou had early-season playoff hopes after a 6-1 start, but the Tigers dropped three of their last five.

Kickoff is at 7:30 p.m. ET from EverBank Stadium in Jacksonville, Fla. The Tigers are 6.5-point favorites, while the over/under is 47.5 in the latest Missouri vs. Virginia odds.

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Before making any Mizzou vs. Virginia picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line picks since the beginning of the 2024 season. Anyone following could have seen impressive returns.

The model has simulated this matchup 10,000 times and the results are in. We can tell you that the model is going Over, and it also says one side of the spread hits 60% of the time!

So who wins Missouri vs. Virginia and which side of the spread hits 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

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