Two Philadelphia Big 5 schools will square off in a season-opening matchup when the Villanova Wildcats battle the La Salle Explorers on Monday evening. The Wildcats (30-8) went to the Final Four last season in Jay Wright's final year as head coach, while the Explorers (11-19) finished 12th in the Atlantic 10.

Tipoff from Finneran Pavilion in Villanova, Pa., is set for 6:30 p.m. ET. Villanova is favored by 15 points at Caesars Sportsbook, while the over-under for total points is set at 137.5 (see up-to-date odds for every game this week on our college basketball odds page).

Before making any Villanova vs. La Salle picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

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Now, it has set its sights on La Salle vs. Villanova. It is leaning Over on the total and it also says one side of the spread hits well over 60% of the time! You ABSOLUTELY need to see it before locking in any college basketball picks.

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