A Big East battle is on tap between the Villanova Wildcats and the DePaul Blue Demons at 8:30 p.m. ET on Wednesday at Finneran Pavilion. DePaul is eyeing a season sweep over Villanova, as the Blue Demons notched a 75-65 victory when these teams met last month. The Wildcats are favored by 9.5 points in the latest Villanova vs. DePaul odds from Caesars Sportsbook, while the over/under is set at 141.5. 

Before you make any DePaul vs. Villanova picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters Week 14 of the season 57-37 on all-top rated college basketball picks this season, returning more than $1,000 for $100 players. Anybody who has followed it has seen HUGE returns.  

Now, it has simulated Villanova vs. DePaul 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Villanova vs. DePaul? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!