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    USC vs. Arizona State odds, line, spread: Proven model reveals college football picks, predictions for Week 5, 2022

    SportsLine's projection model generated CFB picks and predictions for Arizona State Sun Devils vs. USC Trojans
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    A Pac-12 battle is on tap between the No.6 USC Trojans and the Arizona State Sun Devils at 10:30 p.m. ET on Saturday at United Airlines Field at the Los Angeles Memorial Coliseum. USC is 4-0 overall and 2-0 at home, while ASU is 1-3 overall and 0-1 on the road. USC enters off a close 17-14 win at Oregon State while Arizona dropped its Pac-12 opener, 34-13 to No. 13 Utah. The Trojans are favored by 26 points in the latest USC vs. Arizona State odds from Caesars Sportsbook, and the over/under is set at 61. 

    Before you make any Arizona State vs. USC picks, you'll want to see the college football predictions from the SportsLine Projection Model.

    The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns!

    Now, it has simulated USC vs. Arizona State 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it's also generated a point-spread pick that is hitting in over 50% of simulations. You absolutely need to see it before locking in your own picks.

    So who wins USC vs. Arizona State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.

    GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!

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    SportsLine Staff

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