Former lightweight title contenders will meet on Saturday in the main event of UFC 291 when No. 2-ranked Dustin Poirier faces No. 3-ranked Justin Gaethje in a rematch. The main UFC 291 fight card is set for 10 p.m. ET from the Delta Canter in Salt Lake City.

Poirier is a -150 favorite (risk $150 to win $100), while Gaethje comes back at +130 (risk $100 to win $130) in the latest UFC 291: Poirier vs. Gaethje 2 odds from Caesars Sportsbook. Before making any UFC 291 picks, make sure you hear from SportsLine MMA analyst Daniel Vithlani. 

Vithlani is a highly analytical UFC bettor who profited more than 62 units in 2022. This includes a documented 24-14 record on his well-respected, two-leg parlays. Every pick was documented on his public Instagram account (@Brasco_Bets). In his SportsLine debut in January, Vithlani went 5-0 on the main card alone to bring $100 bettors a profit of $500! Anyone who has followed him is WAY UP!

This week at  UFC 291: Poirier vs. Gaethje 2, we can tell you Vithlani is backing Tony Ferguson (+310) to spring the massive upset of Bobby Green (-400) in a lightweight matchup.

Vithlani also has strong picks for Poirier vs. Gaethje 2 and other fights on the UFC 291 card. He's also backing a fighter who "has huge power in his punches and kicks" to emerge with a DOMINANT victory! You ABSOLUTELY need to see his UFC 291 picks before making any of your own!

Who wins UFC 291: Poirier vs. Gaethje 2? And which fighter is a MUST-BACK? Join SportsLine now to see which fighters you need to be all over Saturday, all from the expert who profited a whopping 62 units on MMA picks in 2022!